If you’ve been diagnosed with cold sores or genital herpes, you’ve probably heard of famciclovir. It’s an antiviral pill that can shorten outbreaks and keep the virus from flaring up as often. Unlike creams that sit on the skin, this tablet works inside your body to stop the virus from multiplying.
Famciclovir belongs to a group called nucleoside analogues. After you swallow it, your liver turns it into penciclovir, which then blocks an enzyme the herpes virus needs to copy its DNA. No DNA, no new virus particles, and the outbreak slows down.
The drug is especially good for HSV‑1 (cold sores) and HSV‑2 (genital herpes). Clinical studies show that taking famciclovir within 48 hours of a sore appearing can cut healing time by about half. For people who get frequent outbreaks, a daily suppressive dose can lower the chance of a flare‑up by up to 80%.
Dosage matters. For an initial cold‑sore outbreak, doctors usually prescribe 250 mg three times a day for one day, then twice a day for four more days. For genital herpes, the typical regimen is 250 mg three times daily for ten days during the first episode, and 1 g twice a day for five days if you catch it early.
If you need long‑term suppression, many clinicians recommend 500 mg once daily. Always follow your doctor’s exact schedule; skipping doses can let the virus bounce back.
Take it with food. Famciclovir is easier on the stomach when taken after a meal. If you feel nausea, a small snack can help.
Watch for side effects. Most people only experience mild issues like headache or upset stomach. Rarely, you might notice kidney problems or a rash. Call your doctor if you see swelling, trouble breathing, or unusual bleeding.
Check interactions. The drug can raise levels of certain blood‑thinners (like warfarin) and some HIV medicines. Let your pharmacist know every medication you’re on, including over‑the‑counter supplements.
Pregnant or nursing? Talk to your provider first. While famciclovir is generally considered safe, the doctor will weigh benefits against any potential risks for baby.
Finally, remember that antivirals don’t cure herpes; they just keep it under control. Combine famciclovir with good hygiene—wash hands often, avoid touching sores, and use condoms during sexual activity—to reduce spread.
Got questions about dosing or side effects? Your pharmacist can give quick answers, and your doctor is the best source for personalized advice. With the right plan, famciclovir can make herpes much more manageable.